Rabie is one of the most fatal diseases in both humans and animals. A bite by a rabid dog is the main cause of human rabies. Parenteral mass dog vaccination is the most cost-effective tool to prevent rabies. Research indicates that only a small percentage of African dogs is ownerless. Puppies younger than 3 months of age constitute a considerable proportion of the African dog population. There are considerably more male dogs than female dogs present within the dog population, most dogs in Africa are owned and accessible for vaccination once the necessary financial arrangements have been made.